Macleod’s Clinical Diagnosis 2nd Edition PDF

Macleod's Clinical Diagnosis pdf

Download Macleod’s Clinical Diagnosis – Macleod’s Clinical Diagnosis demonstrates how to apply the core clinical skills learned from the companion textbook Macleod’s Clinical Examination to maximum advantage. Charting the course from routine work-up to diagnosis, this book presents a modern and realistic approach to clinical assessment and explains how to integrate information obtained from the history, examination, bedside tests and specialised investigations.

Macleod’s Clinical Diagnosis

  • The first section Principles of clinical assessment examines different approaches to diagnosis, reviews the fundamental elements necessary for accurate patient assessment, provides a helpful template for a ‘routine workup’ and describes how to adapt the assessment to fit the clinical context.
  • The second core section of the book Assessment of common presenting problems contains a series of ‘diagnostic guides’ that lead the reader, step-by-step through the major presenting problems in medicine and surgery, explaining how to recognise red flag features, eliminate life-threatening conditons and generate a logical differential diagnosis.

This book has been praised as an invaluable resource for senior medical students and junior doctors as they attempt to make the difficult transition from mastering basic clinical skills to assessing patients in the real world of clinical medicine.  

Macleod’s Clinical Diagnosis – Key Features

  • A unique book allowing a reader to apply the skills of clinical examination in the formulation of a differential diagnosis and placing a patient’s symptoms in context.
  • Takes a problem-based approach to diagnostic reasoning, reflecting both modern medical and current educational practices.
  • Builds on the clinical skills outlined in the companion Macleod’s Clinical Examination textbook.

Macleod’s Clinical Diagnosis -Contents

Part 1 Principles of clinical assessment

What’s in a diagnosis?

Assessing patients: a practical guide

The diagnostic processPart 2 Assessment of common presenting problems  

Abdominal pain

Breast lump

Chest pain

Coma and altered consciousness

Confusion: delirium and dementia







GI haemorrhage haemorrhage: haematemesis and rectal bleeding





Joint swelling

Leg swelling

Limb weakness

Low back pain

Mobility problems: falls and immobility

Nausea and vomiting


Rash: acute generalised skin eruption

Red eye

Scrotal swelling


Transient loss of consciousness: syncope and seizures

Urinary incontinence

Vaginal bleeding

Weight loss 


‘Ninety per cent of diagnoses are made from the history.’ ‘Clinical examination is the cornerstone of assessment.’ These, or similar platitudes, will be familiar to most students in clinical training. Many, however, notice a ‘disconnect’ between the importance ascribed to basic clinical skills during teaching and the apparent reliance on sophisticated investigations in the parallel world of clinical practice. Modern diagnostics have radically altered the face of medical practice; clinical training is still catching up. Macleod’s Clinical Diagnosis

We recognize that teachers and textbooks frequently fall into the trap of eulogizing clinical assessment rather than explaining its actual role in contemporary diagnosis. Yet we come to praise the clinical assessment, not to bury it The history may not, by itself, deliver the diagnosis in 90% of cases but it is essential in all cases to generate a logical differential diagnosis and to guide rational investigation and treatment. In many ‘developed’ countries, some so-called classical physica signs are rare and certain aspects of the clinical examination have been marginalized by novel imaging techniques and disease biomarkers.Macleod’s Clinical Diagnosis

Nevertheless, a focused clinical examination is critical to recognizing the sick patient, raising red flags identifying unsuspected problems and, in some cases, revealing signs that cannot be identified with tests (for example, the mental state examination). Our aim is to show you how to use your core clinical skills to maximum advantage. We offer a grounded and realistic approach to clinical diagnosis with no bias towards any particular element of the assessment. Where appropriate, we acknowledge the limitations of the history and examination and direct you to the necessary investigation. Macleod’s Clinical Diagnosis

We also highlight those instances where diagnosis is critically dependent on basic clinical assessment, thereby demonstrating its vital and enduring importance. We wish you every success in your training and practice, and hope that this book provides at least some small measure of assistance


On behalf of the editors and authors, I would like to thank Laurence Hunter for encouraging and facilitating this new edition; and Helen Leng for once again providing the perfect blend of tolerance, support and discipline. We also thank everyone who volunteered suggestions and ideas for the 2nd edition, particularly Dr Vicky Tallen ire, Dr Michael MacMahon and Dr Dean Kerslake. Finally we gratefully acknowledge a valuable contribution to individual chapters from Dr Mark Wright, Consultant Ophthalmologist, Edinburgh (Chapter 28, Red eye); Dr Lydia Ash, Specialty Registrar, Obstetrics & Gynaecology, Edinburgh (Chapter 33, Vaginal bleeding), Mr Andrew Duckworth, Specialty Registrar, Orthopaedic Surgery, Edinburgh (Chapter 20, Joint swelling) and Mr Neil Maitra, Locum Consultant Urologist, Lanarkshire (Chapter 16, Haematuria) and everyone else who has volunteered ideas, comments, assistance or a friendly ear


No. of pages: 328Language: EnglishCopyright: © Elsevier 2018Published: 31st January 2018Imprint: ElsevierPaperback ISBN: 9780702069611Paperback ISBN: 9780702069628eBook ISBN: 9780702069642eBook ISBN: 9780702069635

About the Author

Alan Japp

Affiliations and Expertise

Consultant Cardiologist, Royal Infirmary of Edinburgh; Honorary Clinical Senior Lecturer, University of Edinburgh, UK

Colin Robertson

Affiliations and Expertise

Honorary Professor of Accident and Emergency Medicine and Surgery, University of Edinburgh, Edinburgh, UK

Rohana Wright

Affiliations and Expertise

Consultant Physician, St. John’s Hospital, Livingston and Edinburgh Centre for Endocrinology and Diabetes, Edinburgh, UK.

Matthew Reed

Affiliations and Expertise

Consultant and NRS Career Researcher Clinician in Emergency Medicine, Royal Infirmary of Edinburgh; Honorary Reader, University of Edinburgh, UK.

Andrew Robson

Affiliations and Expertise

Specialist Registrar in General Surgery, Royal Infirmary of Edinburgh, Edinburgh, UK

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