Guyton and Hall Textbook of Medical Physiology 13th Edition

Guyton and Hall Textbook of Medical Physiology 13th Edition pdf

Download Guyton and Hall Textbook of Medical Physiology – The 13th edition of Guyton and Hall Textbook of Medical Physiology continues this bestselling title’s long tradition as the world’s foremost medical physiology textbook.

Guyton and Hall Textbook of Medical Physiology PDF

Unlike other textbooks on this topic, this clear and comprehensive guide has a consistent, single-author voice and focuses on the content most relevant to clinical and pre-clinical students.

The detailed but lucid text is complemented by didactic illustrations that summarize key concepts in physiology and pathophysiology.

Guyton and Hall Textbook of Medical Physiology Features

  • Larger font size emphasizes core information around how the body must maintain homeostasis in order to remain healthy, while supporting information and examples are detailed in smaller font and highlighted in pale blue.
  • Summary figures and tables help quickly convey key processes covered in the text.
  • Bold full-color drawings and diagrams.
  • Short, easy-to-read, masterfully edited chapters and a user-friendly full-color design.
  • Brand-new quick-reference chart of normal lab values on the inside back cover.
  • Increased number of figuresclinical correlations, and cellular and molecular mechanisms important for clinical medicine.
  • Student Consult eBook version included with purchase. This enhanced eBook experience includes the complete text, interactive figures, references, plus 50 self-assessment questions and more than a dozen animations.

Table of Contents

I. Introduction to Physiology: The Cell and General Physiology

1. Functional Organization of the Human Body and Control of the “Internal Environment”

2. The Cell and Its Functions

3. Genetic Control of Protein Synthesis, cell function, and cell reproduction

II. Membrane Physiology, Nerve, and Muscle

4. Transport of Substances Through Cell Membranes

5. Membrane Potentials and Action Potentials

6. Contraction of Skeletal Muscle

7. Excitation of Skeletal Muscle: Neuromuscular Transmission and Excitation-Contraction Coupling

8. Excitation and Contraction of Smooth Muscle

III. The Heart

9. Cardiac Muscle; The Heart as a Pump and Function of the Heart Valves

10. Rhythmical Excitation of the Heart

11. The Normal Electrocardiogram

12. Electrocardiographic Interpretation of Cardiac Muscle and Coronary Blood Flow Abnormalities: Vectorial Analysis

13.Cardiac Arrhythmias and Their Electrocardiographic Interpretation

IV. The Circulation

14. Overview of the Circulation; Biophysics of Pressure, Flow, and Resistance

15. Vascular Distensibility and Functions of the Arterial and Venous Systems

16. The Microcirculation and Lymphatic System: Capillary Fluid Exchange, Interstitial Fluid, and Lymph Flow

17. Local and Humoral Control of Tissue Blood Flow

18. Nervous Regulation of the Circulation and Rapid Control of Arterial Pressure

19. Role of the Kidneys in Long-Term Control of Arterial Pressure and in Hypertension: The Integrated System for Aterial Pressure Regulation

20. Cardiac Output, Venous Return, and Their Regulation

21. Muscle Blood Flow and Cardiac Output During Exercise; the Coronary Circulation and Ischemic Heart Disease

22. Cardiac Failure

23. Heart Valves and Heart Sounds; Valvular and Congenital Heart Defects

24. Circulatory Shock and Its Treatment

V. The Body Fluids and Kidneys

25. The Body Fluid Compartments: Extracellular and Intracellular Fluids; Edema

26. The Urinary System: Functional Anatomy and Urine Formation by the Kidneys

27. Glomerular Filtration, Renal Blood Flow, and Their Control

28. Renal Tubular Reabsorption and Secretion

29. Urine Concentration and Dilution; Regulation of Extracellular Fluid Osmolarity and Sodium Concentration

30. Renal Regulation of Potassium, Calcium, Phosphate, and Magnesium; Integration of Renal Mechanisms for Control of Blood Volume and Extracellular Fluid Volume

31. Acid-Base Regulation

32. Diuretics, Kidney Diseases

VI. Blood Cells, Immunity, and Blood Coagulation

33. Red Blood Cells, Anemia, and Polycythemia

34. Resistance of the Body to Infection: I. Leukocytes, Granulocytes, the Monocyte-Macrophage System, and Inflammation

35. Resistance of the Body to Infection: II. Immunity and Allergy

36. Blood Types; Transfusion; Tissue and Organ Transplantation

37. Hemostasis and Blood Coagulation

VII. Respiration

38. Pulmonary Ventilation

39. Pulmonary Circulation, Pulmonary Edema, Pleural Fluid

40. Principles of Gas Exchange; Diffusion of Oxygen and Carbon Dioxide Through the Respiratory Membrane

41. Transport of Oxygen and Carbon Dioxide in Blood and Tissue Fluids

42. Regulation of Respiration

43. Respiratory Insufficiency – Pathophysiology, Diagnosis, Oxygen Therapy

VIII. Aviation, Space, and Deep-Sea Diving Physiology

44. Aviation, High Altitude, and Space Physiology

45. Physiology of Deep-Sea Diving and Other Hyperbaric Conditions

IV. The Nervous System: A. General Principles and Sensory Physiology

46. Organization of the Nervous System, Basic Functions of Synapses, and Neurotransmitters

47. Sensory Receptors, Neuronal Circuits for Processing Information

48. Somatic Sensations: I. General Organization, the Tactile and Position Senses

49. Somatic sensations: II. Pain, Headache, and Thermal Sensations

X. The Nervous System: B. The Special Senses

50. The Eye: I. Optics of Vision

51. The Eye: II. Receptor and Neural Function of the Retina

52. The Eye: III. Central Neurophysiology of Vision

53. The Sense of Hearing

54. The Chemical Senses – Taste and Smell

XI. The Nervous System: C. Motor and Integrative Neurophysiology

55. Motor Functions of the Spinal Cord; the Cord Reflexes

56. Cortical and Brain Stem Control of Motor Function

57. Contributions of the Cerebellum and Basal Ganglia to Overall Motor Control

58. Cerebral Cortex, Intellectual Functions of the Brain, Learning, and Memory

59. Behavioral and Motivational Mechanisms of the Brain – The Limbic System and the Hypothalamus

60. States of Brain Activity – Sleep, Brain Waves, Epilepsy, Psychoses, and Dementia

61. The Autonomic Nervous System and the Adrenal Medulla

62. Cerebral Blood Flow, Cerebrospinal Fluid, and Brain Metabolism

XII. Gastrointestinal Physiology

63. General Principles of Gastrointestinal Function – Motility, Nervous Control, and Blood Circulation

64. Propulsion and Mixing of Food in the Alimentary Tract

65. Secretory Functions of the Alimentary Tract

66. Digestion and Absorption in the Gastrointestinal Tract

67. Physiology of Gastrointestinal Disorders

XIII. Metabolism and Temperature Regulation

68. Metabolism of Carbohydrates and Formation of Adenosine Triphosphate

69. Lipid Metabolism

70. Protein Metabolism

71. The Liver as an Organ 

72. Dietary Balances; Regulation of Feeding; Obesity and Starvation; Vitamins and Minerals

73. Energetics and Metabolic Rate

74. Body Temperature Regulation and Fever

XIV. Endocrinology and Reproduction

75. Introduction to Endocrinology

76. Pituitary Hormones and Their Control by the Hypothalamus

77. Thyroid Metabolic Hormones

78. Adenocortical Hormones

79. Insulin, Glucagon, and Diabetes Mellitus

80. Parathyroid Hormone, Calcitonin, Calcium and Phosphate Metabolism, Vitamin D, Bone, and Teeth

81. Reproductive and Hormonal Functions of the Male (and Function of the Pineal Gland)

82. Female Physiology Before Pregnancy and Female Hormones

83. Pregnancy and Lactation

84. Fetal and Neonatal Physiology

XV. Sports Physiology

85. Sports Physiology

Review Guyton and Hall Textbook of Medical Physiology

Up to date modern physiology 😀

This is a great physiology textbook! I’m a little over 100 pages in and thought I would leave my thoughts and findings so far. The full online version of the book and resources are included for free! Sixteen video animations, multiple choice questions on each unit of the book, and 25 enhanced images where you can quickly hide the labels, quiz yourself, and then click to see the correct label are all part of the online version resources. There are no quizzes or questions at the end of each unit in the physical print edition (I think the Guyton and Hall Physiology Review 3e is geared toward this aspect). The general layout of the textbook is two columns of text per page with many figures and tables interwoven. The font of the text is clear and easy to read. The text guides you through the figures and explains them well as it is teaching the subject making for a far better learning experience than others where they just have a description underneath the figure (in this textbook there is also a very brief description under the figure but mainly is described in the main part as you are reading). There are mini bibliographies at the end of each unit allowing you to know where you might start to further dive into that topic and read some of the current research papers. Modern research and findings have been seamlessly incorporated. An index is included at the back of this book, but there is no glossary.

Here is the general outline (15 units broken down into 85 chapters):
Unit 1 – Introduction to Physiology: The Cell and General Physiology
Unit 2 – Membrane Physiology, Nerve, and Muscle
Unit 3 – The Heart
Unit 4 – The Circulation
Unit 5 – The Body Fluids and Kidneys
Unit 6 – Blood Cells, Immunity, and Blood Coagulation
Unit 7 – Respiration
Unit 8 – Aviation, Space, and Deep-Sea Diving Physiology
Unit 9 – The Nervous System: A. General Principles and Sensory Physiology
Unit 10 – The Nervous System: B. The Special Senses
Unit 11 – The Nervous System: C. Motor and Integrative Neurophysiology
Unit 12 – Gastrointestinal Physiology
Unit 13 – Metabolism and Temperature Regulation
Unit 14 – Endocrinology and Reproduction
Unit 15 – Sports Physiology

Review

2016 BMA Awards: Highly Commended, Basic & Clinical Sciences

“The 13th edition of Guyton and Hall Textbook of Medical Physiology continues this bestselling title’s long tradition as the world’s foremost medical physiology textbook. Unlike other textbooks on this topic, this clear and comprehensive guide has a consistent, single-author voice and focuses on the content most relevant to clinical and pre-clinical students. The detailed but lucid text is complemented by didactic illustrations that summarize key concepts in physiology and pathophysiology.” -Doody’s Review Service

Preface Guyton and Hall Textbook of Medical Physiology

The first edition of the Textbook of Medical Physiology was written by Arthur C. Guyton almost 60 years ago. Unlike most major medical textbooks, which often have 20 or more authors, the first eight editions of the Textbook of Medical Physiology were written entirely by Dr. Guyton, with each new edition arriving on schedule for nearly 40 years. Dr. Guyton had a gift for communicating complex ideas in a clear and interesting manner that made studying physiology fun. He wrote the book to help students learn physiology, not to impress his professional colleagues. I worked closely with Dr. Guyton for almost 30 years and had the privilege of writing parts of the ninth and tenth editions. After Dr. Guyton’s tragic death in an automobile accident in 2003, I assumed responsibility for completing the subsequent editions. Guyton and Hall Textbook of Medical Physiology

For the thirteenth edition of the Textbook of Medical Physiology, I have the same goal as for previous editions— to explain, in language easily understood by students, how the different cells, tissues, and organs of the human body work together to maintain life. This task has been challenging and fun because our rapidly increasing knowledge of physiology continues to unravel new mysteries of body functions. Advances in molecular and cellular physiology have made it possible to explain many physiology principles in the terminology of molecular and physical sciences rather than in merely a series of separate and unexplained biological phenomena. The Textbook of Medical Physiology, however, is not a reference book that attempts to provide a compendium of the most recent advances in physiology. This is a book that continues the tradition of being written for students. It focuses on the basic principles of physiology needed to begin a career in the health care professions, such as medicine, dentistry, and nursing, as well as graduate studies in the biological and health sciences. It should also be useful to physicians and health care professionals who wish to review the basic principles needed for understanding the pathophysiology of human disease. Guyton and Hall Textbook of Medical Physiology

I have attempted to maintain the same unified organization of the text that has been useful to students in the past and to ensure that the book is comprehensive enough Preface that students will continue to use it during their professional careers. My hope is that this textbook conveys the majesty of the human body and its many functions and that it stimulates students to study physiology throughout their careers. Physiology is the link between the basic sciences and medicine. The great beauty of physiology is that it integrates the individual functions of all the body’s different cells, tissues, and organs into a functional whole, the human body. Indeed, the human body is much more than the sum of its parts, and life relies upon this total function, not just on the function of individual body parts in isolation from the others. This brings us to an important question: How are the separate organs and systems coordinated to maintain proper function of the entire body? Fortunately, our bodies are endowed with a vast network of feedback controls that achieve the necessary balances without which we would be unable to live. Physiologists call this high level of internal bodily control homeostasis. In disease states, functional balances are often seriously disturbed and homeostasis is impaired. When even a single disturbance reaches a limit, the whole body can no longer live. One of the goals of this text, therefore, is to emphasize the effectiveness and beauty of the body’s homeostasis mechanisms as well as to present their abnormal functions in disease. Guyton and Hall Textbook of Medical Physiology

Another objective is to be as accurate as possible. Suggestions and critiques from many students, physiologists, and clinicians throughout the world have checked factual accuracy as well as balance in the text. Even so, because of the likelihood of error in sorting through many thousands of bits of information, I wish to issue a further request to all readers to send along notations of error or inaccuracy. Physiologists understand the importance of feedback for proper function of the human body; so, too, is feedback important for progressive improvement of a textbook of physiology. To the many persons who have already helped, I express sincere thanks. Your feedback has helped to improve the text. A brief explanation is needed about several features of the thirteenth edition. Although many of the chapters have been revised to include new principles of physiology and new figures to illustrate these principles, the text length has been closely monitored to limit the book size so that it can be used effectively in physiology courses for medical students and health care professionals. Many of the figures have also been redrawn and are in full color. New references have been chosen primarily for their presentation of physiological principles, for the quality of their own references, and for their easy accessibility. The selected bibliography at the end of the chapters lists papers mainly from recently published scientific journals that can be freely accessed from the PubMed site at http://www.ncbi.nlm.nih.gov/pubmed/. Use of these references, as well as cross-references from them, can give the student almost complete coverage of the entire field of physiology. The effort to be as concise as possible has, unfortunately, necessitated a more simplified and dogmatic presentation of many physiological principles than I normally would have desired. However, the bibliography can be used to learn more about the controversies and unanswered questions that remain in understanding the complex functions of the human body in health and disease. Another feature is that the print is set in two sizes. The material in large print constitutes the fundamental physiological information that students will require in virtually all of their medical activities and studies. The material in small print and highlighted with a pale blue background is of several different kinds: (1) anatomic, chemical, and other information that is needed for immediate discussion but that most students will learn in more detail in other courses; (2) physiological information of special importance to certain fields of clinical medicine; and (3) information that will be of value to those students who may wish to study particular physiological mechanisms more deeply. I wish to express sincere thanks to many persons who have helped to prepare this book, including my colleagues in the Department of Physiology and Biophysics at the University of Mississippi Medical Center who provided valuable suggestions. The members of our faculty and a brief description of the research and educational activities of the department can be found at http://physiology .umc.edu/. I am also grateful to Stephanie Lucas for excellent secretarial services and to James Perkins for excellent illustrations. Michael Schenk and Walter (Kyle) Cunningham also contributed to many of the illustrations. I also thank Elyse O’Grady, Rebecca Gruliow, Carrie Stetz, and the entire Elsevier team for continued editorial and production excellence. Finally, I owe an enormous debt to Arthur Guyton for the great privilege of contributing to the Textbook of Medical Physiology for the past 25 years, for an exciting career in physiology, for his friendship, and for the inspiration that he provided to all who knew him.

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Details

No. of pages: 1168Language: EnglishCopyright: © Saunders 2016Published: 20th May 2015Imprint: SaundersHardcover ISBN: 9781455770052Paperback ISBN: 9781455770168eBook ISBN: 9780323389587eBook ISBN: 9780323389570eBook ISBN: 9780323389303eBook ISBN: 9780323389556


About the Authors

John Hall Author

Affiliations and Expertise

Arthur C. Guyton Professor and Chair, Department of Physiology and Biophysics, Director, Mississippi Center for Obesity Research, University of Mississippi Medical Center, Jackson, Mississippi

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