Genetic Variability Parasites and Host-parasite Interactions By R. C. A. Thompson and A. J. Lymber PDF
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\Ve have examined genetic variability in parasites in the context of ecological interactions with the host. Recent research
on Echinococcus, Giardia and Cryptosporidium has been used to illustrate: (i) the problems that parasite variability and
species recognition pose for understanding the complex and often controversial relationship between parasite and host
occurrence; (ii) the need for accurate parasite characterization and the application of appropriate molecular techniques to
studies on parasite transmission if fundamental questions about zoonotic relationships and risk factors are to be answered;
(iii) our lack of understanding about within-host interactions between genetically heterogeneous parasites at the inter- and
intraspecific levels, and the significance of such interactions with respect to evolutionary considerations and the clinical
outcome of parasite infections. If advances in molecular biology and mathematical ecology are to be realized, we need to
give serious consideration to the development of appropriate species concepts and in vivo systems for testing the predictions and assumptions of theoretical models.