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Essentials of Clinical Pathology by Kawthalkar Shirish M PDF

Essentials of Clinical Pathology explains the basic fundamentals of clinical chemistry, laboratory tests in diagnosis and management of diseases. It is mainly intended for second MBBS students and postgraduate residents in pathology. It will also be an essential reading for students of medical laboratory technology.

Its main strengths are easy readability, scientific basis, incorporation of most recent concepts, and clinical relevance. Discussion of laboratory tests is preceded, where required, by basic information on anatomy, physiology, and a concise outline of relevant diseases to facilitate understanding.

The book is organized in Three Sections which are further divided into 39 chapters. Key information is emphasized by numerous illustrations, tables, and boxes. Reference ranges and critical values have been incorporated at the end of each chapter for quick access.

Preface – Essentials of Clinical Pathology

The major aims of this book are discussion of (i) use of laboratory tests in the investigation and management of common diseases, and (ii) basic biochemical and pathological principles underlying the application of laboratorytests. The book has been written keeping in mind mainly the curricula of undergraduate students of pathology. Itshould also prove to be appropriate for postgraduate residents and students of medical laboratory technology. Essentials of Clinical Pathology

The laboratory tests that are demonstrated to and performed by medical students in pathology practical class and during university examination are given in more detail. To keep pace with new knowledge and advances, principles of currently performed techniques in clinical laboratory practice have also been outlined. Most of the chapters are followed by reference ranges and critical values for ready access. Critical values or action values are those laboratory results that require immediate attention of the treating clinician. While interpreting results of laboratory tests, it is necessary to follow two fundamental rules of laboratory medicine: (i) diagnosis should never be made from a single abnormal test result (since it is affected by a number of pre analytical and analytical factors), and (ii) try to arrive ata single diagnosis (rather than multiple diagnoses) from all the abnormal test results obtained.Clinical pathology is the second major subdivision of the discipline of pathology after anatomic pathology. It is concerned with laboratory investigations for screening, diagnosis, and overall management of diseases by analysis of blood, urine, body fluids, and other specimens. The specialties included under the discipline of clinical pathology are clinical chemistry, hematology, blood banking, medical microbiology, cytogenetics, and molecular genetics.However, scope of this book does not allow microbiology and genetics to be included in this book.I must appreciate and recognize the unstinting support of my parents, my beloved wife Dr Anjali, and my twochildren, Ameya and Ashish during preparation of this book. Essentials of Clinical Pathology

I am thankful to Dr HT Kanade, Dean, Government Medical College, Akola, Dr Smt Deepti Dongaonkar, Dean, Government Medical College, Nagpur, Dr BB Sonawane,Professor and Head, Department of Pathology, Government Medical College, Akola, and Dr WK Raut, Professor and Head, Department of Pathology, Government Medical College, Nagpur, for encouraging me in undertaking this project for the benefit of medical students.I express my thanks to Mr JP Vij and his outstanding team of M/s Jaypee Brothers Medical Publishers for under taking to publish this book, being patient with me during the preparation of the manuscript, and bringing it out in an easy-to-read and reader-friendly format.Although I have made every effort to avoid any mistakes and errors, some may persist and feedback in this regard will be highly appreciated. Shirish M Kawthalkar

TABLE OF CONTENTS: – Essentials of Clinical Pathology

Section 1: Chemical Pathology and Related Studies

  • Examination of Urine
  • Renal Function Tests
  • Diabetes Mellitus
  • Liver Function Tests
  • Disorders of Lipids and Biochemical Cardiac Markers
  • Examination of Cerebrospinal Fluid
  • Examination of Pleural and Peritoneal Fluids
  • Examination of Sputum
  • Examination of Feces
  • Gastric Analysis
  • Tests for Malabsorption and Pancreatic Function
  • Thyroid Function Tests
  • Pregnancy Tests
  • Infertility
  • Semen Analysis

Section 2: Laboratory Hematology, Essentials of Clinical Pathology

  • Hematopoiesis
  • Collection of Blood
  • Estimation of Hemoglobin
  • Packed Cell Volume
  • Total Leukocyte Count
  • Reticulocyte Count
  • Blood Smear
  • Red Cell Indices
  • Erythrocyte Sedimentation Rate
  • Examination of Bone Marrow
  • Diagnosis of Malaria and Other Parasites in Blood
  • Laboratory Tests in Anemia
  • Laboratory Tests in Hematological Malignancies
  • Laboratory Tests in Bleeding Disorders
  • Laboratory Tests in Thrombophilia
  • Laboratory Tests in Porphyrias
  • Automation in Hematology,

Section 3: Practical Blood Transfusion, Essentials of Clinical Pathology

  • Blood Group Systems
  • Blood Grouping
  • Collection of Donor Blood, Processing and Storage
  • Screening Tests for Infections ransmissible by Transfusion
  • Compatibility Test (Cross-match)
  • Adverse Effects of Transfusion
  • Blood Components.

About the Author – Essentials of Clinical Pathology

Shirish M Kawthalkar
Associate Professor, Department of Pathology, Government Medical College, Nagpur, Maharashtra, India

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