Harrison’s Rheumatology – Featuring a superb compilation of chapters related to rheumatology derived from Harrison’s Principles of Internal Medicine, Nineteenth Edition (including content from the acclaimed Harrison’s DVD, now available here in print), this concise, full-color clinical companion delivers the latest knowledge in the field backed by the scientific rigor and authority that have defined Harrison’s.
You will find 24 chapters from more than 35 renowned editors and contributors in a carry-anywhere presentation that is ideal for the classroom, clinic, ward, or exam/certification preparation.
Table of Contents
FEATURES – Harrison’s Rheumatology
• Current, thorough coverage of important immunology and rheumatology topics, including the immune system in health and disease, disorders of immune-mediated injury, and disorders of the joints and adjacent tissues
• Delivers insights designed to reduce pain, lesson joint and organ damage, and improve overall patient outcomes
• Integrates pathophysiology with clinical management
• High-yield board review questions make this text ideal for keeping current and preparing for the boards
• Helpful appendix of laboratory values of clinical importance
PREFACE – Harrison’s Rheumatology
Arthritis and its related musculoskeletal disorders constitute the most common chronic
illnesses in the United States. These conditions adversely affect the quality of life of those
who are struck by them, require increased use of health care resources, and, because they are
the leading cause of disability in the United States, have a significant impact on the national
economy. Physicians and other health care workers in many disciplines have been involved in
the care and study of patients with these diseases. As a result, our understanding of and
ability to treat these diseases have improved continuously.
This Atlas of Rheumatology is designed to help clinicians learn about this group of
diseases and develop an understanding of their possible causes, clinical features, laboratory
findings, and treatments, using an attractive pictorial format. Because more than 100 sepa-
rate types of arthritis have been described, unfortunately all could not be included. The illus-
trations shown in the Atlas have been carefully selected by recognized experts, who served
as authors of the eight chapters, to provide the reader with the essential information needed
to get a clear picture of these important diseases. For their successful efforts I am deeply
grateful. I am also indebted to editorial workers who have maintained high standards to
create a clear, attractive final product.
CONTENTS – Harrison’s Rheumatology
Rheumatoid Arthritis, Juvenile Rheumatoid Arthritis, and
Related Conditions
Eric L Matteson
Rheumatoid Arthritis …. 1.2
Juvenile Rheumatoid Arthritis 1.32
Related Conditions ] 38
CHAPTER 2
Osteoarthritis and Crystal-Associated Synovitis
Stephen L Myers
Osfeonrfhnfts 2.2
Secondary Osteoarthritis 2.8
Management and Therapy of Osteoarthritis 2.13
Gout 2.14
CHAPTER 3
Systemic Lupus Erythematosus, Antiphospholid Syndrome, Scleroderma,
and Inflammatory Myopathies
Graham R.V. Hughes and Munther A. Khamashta
St/sfemic Lupus Erythematosus… 3.2
Antiphospholipid (Hughes’) Syndrome 3.15
Scleroderma 3.19
Idiopathic Inflammatory Myopathies … 3.23
CHAPTER 4 Harrison’s Rheumatology
Vasculitides
LoVc Guillevin
Clossi^carion 4.2
Polyarteritis Nodosa. 4.6
Microscopic Polyangiitis 4.10
Churg-Strauss Syndrome …..4.12
Wegener’s Granulomatosis 4.14
Behcet’s Disease 4. 18
Thkayasu Arfer/ris 4.20
Giant Cell Arteritis 4.22
Henoch-Schonlein Purpura 4,24
Cryoglobulinemia 4.25
Virus-Associated Vasculitis 4.28
Vasculitides Associated with Malignancy 4.30
Vasculitis Associated unth Rheumatoid Arthritis 4.31
TYeatment of Vasculitis 4.32
Ocular Vasculitis 4.36
CHAPTER 5 Harrison’s Rheumatology
Spondyloarthropathies
Muhammed Asim Khan
Classification , Criteria, and Prevalence 5.3
Ankylosing Spondylitis 5.6
Reactive Arthritis 5.19
Psoriasis 5.21
Miscellaneous Forms of Disease 5.23
CHAPTER 6
Disease of Bone and Connective Tissue
Michael J. Maricic and Marcia Ko
Osteoporosis 6.2 Harrison’s Rheumatology
Primary and Secondary Hyperparathyroidism and Osteomalacia 6. 7
Paget’s Disease of Bone 6.10
Osteonecrosis and Avascular Necrosis 6.13
Disorders of Collagen Metabolism 6.14
Sclerotic Bone Disorders 6.16
CHAPTER 7
Infectious Arthritis
Leonard Sigal
Nongonococcal Septic Arthritis 7.2
Viral Arthritides 7.4
Mycobacteria 7.5
Gonococcal Arthritis 7.6
Charcot (Neuropathic) Joint 7.8
Lyme Disease 7.9
CHAPTER 8
Arthritis and Systemic Disease
Kenneth T. Calamia, Marc D. Cohen, and David M. Menke
Amyloidosis 8.2
Hemophilic Arthropathy 8.5
Hemoglobinopathies and Arthritis: Sickle Cell Disease and Thalassemia 8. 7
Myeloproliferative Disorders 8.8
Hemochromatosis 8.8
Hypertrophic Osteoarthropathy 8.11
Neoplastic Lesions of Joints and Related Structures 8.13
Arthropathies with Endocrine Disorders 8.16
Miscellaneous Diseases with Arthritis 8.17
Index 1.1 Harrison’s Rheumatology
About the Author
Anthony S. Fauci, MD (Bethesda, MD) is Director, National Institute of Allergy and Infectious Diseases, NIH.
Carol Langford, MD (Cleveland, OH) Director of the Vasculitis Center, Cleveland Clinic Foundation.
